
“Pathogenic mAbs, large metastable immune complexes and activated platelets: mass
spectrometry reveals the mechanism of a deadly vaccine side effect”
Igor A. Kaltashov
Genentech, Roche Group – USA
Igor A. Kaltashov received his undergraduate degree in Physics at Moscow Institute of Physics and Technology in 1989 and a Ph.D. from the University of Maryland Baltimore County in 1996.
After two years as a post-doctoral fellow at Johns Hopkins Medical School, he joined the University of Massachusetts-Amherst in 1997, where he is now a Professor in the Chemistry Department.
His research focuses on developing mass spectrometry-based experimental techniques to study structure, conformation, dynamics, and interactions of biopolymers. His group has collaborated with biopharmaceutical companies, including Amgen, Biogen, and Pfizer.
Prof. Kaltashov has co-authored over 150 papers and book chapters and has guest-edited special issues for various journals, including the most recent “Mass spectrometry-based methods to study macromolecular higher-order structure and interactions” for Methods.
He also co-authored “Mass Spectrometry in Biophysics: Conformation and Dynamics of Biomolecules”, whose second edition was published in 2012, and his most recent book, “Mass Spectrometry in Biopharmaceutical Analysis”, written with two of his former graduate students, was published in 2022.